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September 04.2025
2 Minutes Read

Insurance Struggles With GLP-1 Drug Costs: A Shift Towards Deprescription

Close-up of a hand holding a 'zepbound' injection pen, highlighting GLP-1 drug costs.

The Rising Costs of GLP-1 Medications

The use of GLP-1 drugs for weight loss and Type 2 diabetes management has surged, but so have their costs. Drugs like Zepbound, Wegovy, and Ozempic now have list prices that can reach approximately $1,000 a month. These exorbitant costs are forcing insurers to reconsider their coverage options. For example, North Carolina's Medicaid program plans to discontinue coverage for weight loss applications of GLP-1s effective October 1, marking a swift reversal just over a year after launching this coverage. This decision reflects broader national trends among public and private payers facing financial pressures amidst rising demand.

Insurance Challenges and Patient Impact

The thirst for these drugs is often dampened by barriers such as insurance coverage denials. Patients like Kyra Wensley, who initially lost weight effectively on Zepbound, found themselves compelled to switch medications due to insurance policies that restricted access based on specific BMI thresholds. For those who rely on these medications for sustained weight loss, such transitions can feel like a loss, raising questions about fairness and accessibility in healthcare.

Deprescription: A Cost-Saving Strategy?

As insurers grapple with rising GLP-1 costs, a notable approach is emerging: deprescription. This strategy involves tapering patients off medications once health goals are met or after a set timeframe. Advocates, including A. Mark Fendrick from the University of Michigan, argue that this could potentially extend access to these life-changing drugs to a broader population. By adopting more strategic treatment timelines for certain patients, resources could be allocated more effectively.

The Future of GLP-1 Coverage

While some states are pulling back on GLP-1 coverage, there are discussions among federal officials about potential pilot programs to improve access under Medicaid and Medicare. As the dialogue continues about the sustainability of these drug programs, it is crucial to balance cost factors with the health benefits these medications provide. If the healthcare system can evolve around both innovative treatments and sensible financial policies, we might see a more inclusive approach to obesity treatment that benefits all patients.

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